Statements

“This conference will bring together experts from many different cellular, molecular and systems perspectives of brain injury and repair for what should be great discussions, at a time in which many basic scientific principles are now ripe for consideration as translational concepts for human therapies.”

Thomas Carmichael
Los Angeles, University of California

"Neuroprotection is one most important challenge to protect our brain from many injuries including ischemic stroke. However, many neuroprotective drugs have failed to show positive clinical effect for acute stroke patients. A free radical scavenger edaravone is an exception of such drugs which was developed in Japan, and successfully showed a clinical effect on acute ischemic stroke. The importance of a neuroprotective drug is emerging with use of tissue plasminogen activator (tPA) in acute stroke patients. The molecular mechanism of edaravone is not simply the free radical scavenging effect but also protective effect on neurovascular unit. On the other hand, stem cells are very important candidate to repair injured brain and restore brain function after injury such as stroke. iPS (induced pluripotent stem) cells are recognized as a promising tool for such brain repair after the injury. Current study in my department with iPS cells will be reported in this symposium."

Koji Abe
Okayama, University of Okayama

"There is a huge unmet need of new stroke therapies. At the 6th International Symposium on Neuroprotection and Neurorepair we will here the most recent research results in the field of stroke. Those interested in stroke research this meeting is a must."

Tadeusz Wieloch
Lund, University of Lund

"An impressive meeting providing a comprehensive appraisal of cutting-edge stroke research."



Costantino Iadecola
New York, Weill Medical College of Cornell University

"Recent experimental and clinical results from our as well as other laboratories support the idea that in acute stroke, spreading depolarisations circle around evolving ischemic lesions. We discuss that they may be part of both damage and repair mechanisms in the border zone of these lesions, the ischemic penumbra."

Rudolf Graf
Köln, Max-Planck-Institute for Neurological Research

Brain protection and repair: the ultimate frontiers of translational neuroscience. Let's meet there!

Ulrich Dirnagl
Berlin, Charité - Universitätsmedizin

"This conference offers a wonderful opportunity to meet, discuss and interact with international experts in different areas of neural repair. The program includes a great mix of topics ranging from molecular to cellular to systems level approaches. Our presentation will examine how genetic tools are enabling the molecular dissection of the functions and mechanisms of reactive astrogliosis in vivo."

Michael Sofroniew
Los Angeles, University of California

"This year again, the organising Comittee has managed to bring together an incredible panel of scientists to the Neuroprotection & Neurorepair Symposium. This is a unique opportunity to reflect on where we are and where we are going in our specialised domain and to get a state-of-the-art overview of the many aspects of stroke."

Brigitte Onteniente
Paris, Institut National de la sante et de la recherche Medicale

“We are looking forward to a conference that will bring together some of the most brilliant minds and cutting edge researchers with enthusiastic young scientists in the field of cerebral ischemia and stroke from all over the world. We are looking forward to excellent scientific sessions, stimulating discussions and interesting poster presentations from basic research to translational stroke medicine in a breathtaking environment. And we are looking forward to welcome you, too!”

Johannes Boltze
Leipzig, Fraunhofer Institute for Cell Therapy and Immunology

“Stem cells can give rise to functional improvements after stroke by several mechanisms but many issues, which will be discussed at the conference, remain before stem cell-based approaches can advance to full-scale clinical trials in stroke patients.”

Olle Lindvall
Lund, Lund University Hospital

“Time is brain”

Denis Vivien
Caen Cedex, Université de Caen

"This important meeting on neuroprotection and neurorepair reflects the most recent basic and translational research in the context of cerebrovascular and neurodegenerative diseases and is a must for students, postdocs and seniors.”

Wolf Schäbitz
Bielefeld, Evangelisches Krankenhaus Bielefeld

"The concept of neurorepair after ischemic stroke is gradually gaining the importance that has already been afforded to neuroprotection. Therefore, I cannot think of a better opportunity than this meeting to bring together experts in both areas to stimulate thinking on novel approaches to stroke therapy."


Gregory J. Bix
Texas, Department of Molecular and Cellular Medicine &
Neuroscience and Experimental Therapeutics

"Neuroprotection and Neurorepair is an emerging new field in the study of neurodegenerative diseases.  This field encompasses a basic understanding of mechanisms underlying neurodegenerative diseases, and the physiological and pharmacological mechanisms required for treating them, ranging between immunological, cellular, molecular, and genetic approaches.  Key questions will be discussed relating to the role of inflammation, and the enigma of the different roles played by resident microglia and infiltrating blood-borne macrophages, despite their similar primary origin. In addition, issues such as why anti-inflammatory drugs have shown disappointing results in treating these diseases will be addressed, as well.  The upcoming meeting covers a broad range of topics in this emerging new field, and will include an outstanding selection of experts in each aspect of the field.  Such a multidisciplinary meeting and its associated discussions are expected to result in novel ideas and directions for therapy."

Michal Schwartz
Rehovot, The Weizmann Institute of Science

"While ~3% of the mammalian genome forms protein-coding mRNAs, the remaining 97% forms several classes of non-protein coding RNAs. In particular, evolutionarily well-conserved small non-coding RNAs known as microRNAs control protein translation and thus brain function. Our lab is evaluating the significance of cerebral microRNAome in mediating the post-ischemic pathophysiologic events like inflammation and cell death. Our long-term goal is to develop novel non-coding RNA-based therapies to prevent secondary brain damage."

Raghu Vemuganti
Madison, University of Wisconsin

“The 6th International Symposium on Neuroprotection and Neurorepair looks interesting and exciting.  International experts in neuroprotection and neurorepair will be present to present state of the art work and participate in discussions throughout the meeting.  I look forward to this meeting very much."

Richard J.Traystman
Denver, University of Colorado Denver

„Clearly, the field of Regenerative Medicine will benefit most from the emerging new imaging and optical stimulation methods. It should be feasible to both image and control e.g. stem cells upon transplantation. This conference will provide a unique platform to discuss those new ideas in an interdisciplinary setting.”

Albrecht Stroh
München, Technische Universität München